Recent research shows that periodontal regeneration is no exception. 2014 Jun;85(6):845-51. doi: 10.1902/jop.2013.130254. 8, 9, 10 This has opened the way for new cell-based therapies for periodontal regeneration. Periodontal Regeneration PRESENTED BY: PRABLEEN ARORA MDS STUDENT 2. Editors and affiliations. Epub 2013 Sep 3. TERMINOLOGY (acc.to glossary of periodontal terms) A graft is any tissue or organ used for implantation or transplantation. Induced Pluripotent Stem Cells: A New Frontier for Stem Cells in Dentistry. NIH Epub 2013 Sep 23. The clinical treatment of defects usually consists … These conventional membranes possess many structural, mechanical, and bio-functional limitations and the “ideal” membrane for use in periodontal regenerative therapy has yet to be developed. 2019 Oct;98(11):1173-1182. doi: 10.1177/0022034519861903. They are applied in the procedures where severe periodontium defects need to be reconstructed. The main symposium themes included recent advances in the diagnosis and treatment of periodontal diseases, chemical plaque control of gingivitis and periodontal disease, reappraisal of longitudinal studies, new surgical approaches to the regeneration of periodontal tissues and the periodontal application of dental implants. The benefits are seen mainly in patients with diabetes or metabolic syndrome, which point to an altered inflammatory profile (read more at: agencia.fapesp.br/34357). The use of an occlusive membrane interfacing with gingival connective tissue/epithelium and a PDL/alveolar bone tissue to promote periodontal tissue regeneration is called GTR. The clinical treatment of defects usually consists … Background: … cementum, alveolar bone and periodontal ligament. J Dent Res. Young-Dan Cho, Kyoung-Hwa Kim, Hyun-Mo Ryoo, Yong-Moo Lee, Young Ku, Yang-Jo Seol, Recent Advances of Useful Cell Sources in the Periodontal Regeneration, Current Stem Cell Research & Therapy, 10.2174/1574888X13666180816113456, 14, 1, (3-8), (2019). A plethora of different surgical … Specifically, this report mentions three new advances in regeneration. The Dr. James T. Mellonig Regeneration Research Award recognizes excellence in original research by a resident in the specialty of periodontics that advances clinical therapies in periodontal regeneration. eCollection 2020. Copyright © 2012 Academy of Dental Materials. Cho YD (1), Kim KH (1), Ryoo HM (2), Lee YM (1), Ku Y (1), Seol YJ (1). Published by Elsevier Ltd. All rights reserved. on this extent, i have tried to provide the reader with a compilation of superior information of surgical periodontal therapy. This site needs JavaScript to work properly. ScienceDirect ® is a registered trademark of Elsevier B.V. ScienceDirect ® is a registered trademark of Elsevier B.V. NLM Objectives and Results: In this review, we consider all available stem cell sources, methods to obtain the cells, their capability to differentiate into the desired cells, and the extent of their utilization in periodontal regeneration. Conclusions: There are recent advances in periodontal surgical techniques, from resection to regeneration, the focus of surgical access has shifted to regeneration of lost tissues. In addition, we introduce the new concepts of using iPSCs and transdifferentiated cells for periodontal regeneration. Recent advances in periodontal regeneration: A biomaterial perspective, Bioactive Materials, 10.1016/j.bioactmat.2020.02.012, 5, 2, (297-308), (2020). An occlusive membrane acts as a barrier when placed into the surgical site, preventing connective and epithelial tissue migration into the defect. New understanding of the tissues involved in regeneration and of the materials used to promote regeneration have led to new advances. Epub 2015 Aug 18. Please enable it to take advantage of the complete set of features! An autograft is a tissue transferred from one position to a new position in the same individual. 33 The first report about the isolation and characterization of periodontal ligament stem cells was published in 2004, and since then the field of dental stem cells has advanced quickly, particularly with regard to its potential use for periodontal … COVID-19 is an emerging, rapidly evolving situation. Epub 2015 Jan 2. To date, flap debridement and/or flap curettage and periodontal regenerative therapy with membranes and bone grafting materials have been employed with distinct levels of clinical success. Periodontitis is an inflammatory disease that can result in destruction of the tooth attachment apparatus. Like many factors of fitness care, technological innovations in materials technological know-how, in addition to improvement of new tools and techniques, pressure advances in periodontal remedy. Recent advances have enumerated the presence of adult stem cells in periodontal ligament of humans and other animals. Would you like email updates of new search results? Electronic databases (Pubmed, Web of Science) were searched up to February 2020. Stem cells; cell reprogramming; induced pluripotent stem cells; periodontal tissue regeneration; tissue engineering; trans-differentiation.. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net. Approaches using stem cells and reprogrammed cells, such as induced pluripotent stem cells (iPSCs) or trans-differentiated cells, represent the cutting edge in periodontal regeneration, and have led to many trials for their clinical application. 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